PENGARUH DETERMINAN PSIKOSOSIAL TERHADAP PERILAKU KEPATUHAN PENGOBATAN  PADA PENDERITA DIABATES MELITUS TIPE 2

Authors

  • Rondhianto Fakultas Keperawatan, Universitas Jember
  • Murtaqib Fakultas Keperawatan, Universitas Jember
  • Nicky Septiana Putri  Fakultas Keperawatan, Universitas Jember

DOI:

https://doi.org/10.21776/majalahkesehatan.2025.012.01.2

Keywords:

diabetes melitus tipe 2, faktor psikososial, perilaku kepatuhan pengobatan

Abstract

Diabetes melitus tipe 2 (DMT2) merupakan penyakit kronis yang membutuhkan pengelolaan mandiri secara berkesinambungan. Kepatuhan pengobatan merupakan bagian penting dari pengelolaan mandiri untuk meningkatkan kontrol metabolik sehingga dapat meningkatkan hasil pengelolaan diabetes. Faktor psikososial, seperti pengetahuan, koping, distres, dukungan keluarga, dan dukungan perawat merupakan determinan perilaku kepatuhan pengobatan dengan hasil yang inkonsisten. Penelitian ini bertujuan untuk menganalisis pengaruh faktor psikososial terhadap perilaku kepatuhan pengobatan pada penderita DMT2. Desain penelitian adalah observasional analitik dengan cross-sectional design. Sampel berjumlah 138 responden yang diambil secara multistage random sampling. Faktor psikososial sebagai variabel independen, sedangkan variabel dependen adalah perilaku kepatuhan pengobatan. Data dikumpulkan dengan kuesioner (SKILLD, coping scale, DDS, HDFSS, dukungan perawat, dan MMAS) yang sudah valid dan reliabel, serta dianalisis secara deskriptif dan inferensial dengan uji regresi liner berganda. Hasil menunjukkan 58,68% responden mempunyai kepatuhan pengobatan yang rendah. Pengetahuan, distres, dukungan keluarga, dukungan perawat dalam kategori sedang (58,70%; 69,57%; 53,62%; 63,77%). Sedangkan koping berada dalam kategori rendah (68,84%). Analisis inferensial menunjukkan bahwa pengetahuan, koping, distres, dukungan keluarga, dan dukungan perawat secara simultan berpengaruh sebesar 43,9% terhadap perilaku kepatuhan pengobatan (F = 22.456; p = 0,001; adjusted R2 = 0,439). Secara parsial, hanya pengetahuan dan koping yang mempunyai pengaruh signifikan terhadap perilaku kepatuhan pengobatan (t = 3,788; t = 8,299; p = 0,001). Kesimpulan penelitian adalah faktor psikososial merupakan determinan perilaku kepatuhan pengobatan penderita DMT2. Oleh karena itu, upaya peningkatan perilaku kepatuhan pengobatan oleh tenaga kesehatan hendaknya dilakukan dengan mempertimbangkan faktor psikososial, terutama peningkatan pengetahuan dan koping sehingga dapat meningkatkan pengelolaan mandiri DMT2 sebagai bagian tatalaksana diabetes secara komprehensif.

Author Biographies

  • Rondhianto, Fakultas Keperawatan, Universitas Jember

    Departemen Keperawatan Medikal Bedah dan Kritis

  • Murtaqib, Fakultas Keperawatan, Universitas Jember

    Departemen Keperawatan Medikal Bedah dan Kritis

  • Nicky Septiana Putri,  Fakultas Keperawatan, Universitas Jember

    Departemen Keperawatan Medikal Bedah dan Kritis

References

ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, Collins BS, Hilliard ME, Isaacs D, Johnson EL, Kahan S, Khunti K, Leon J, Lyons SK, Perry ML, Prahalad P, Pratley RE, Seley JJ, Stanton RC, Gabbay RA, on behalf of the American Diabetes Association. 2. Classification and Diagnosis of Diabetes: Standards of Care in Diabetes-2023. Diabetes Care. 2023 Jan 1;46(Suppl 1):S19-S40. doi: 10.2337/dc23-S002. Erratum in: Diabetes Care. 2023 May 1;46(5):1106. doi: 10.2337/dc23-er05. Erratum in: Diabetes Care. 2023 Sep 01;46(9):1715. doi: 10.2337/dc23-ad08

Dianna J. Magliano, Co-chair, Edward J. Boyko, Co-chair; IDF Diabetes Atlas 10th Edition Scientific Committee. Brussels: International Diabetes Federation; 2021.

Aloudah NM, Scott NW, Aljadhey HS, Araujo-Soares V, Alrubeaan KA, Watson MC. Medication Adherence Among Patients with Type 2 Diabetes: A Mixed Methods Study. PLoS One. 2018 Dec 11;13(12):e0207583. doi: 10.1371/journal.pone.0207583

Mirahmadizadeh A, Khorshidsavar H, Seif M, Sharifi MH. Adherence to Medication, Diet and Physical Activity and the Associated Factors Amongst Patients with Type 2 Diabetes. Diabetes Ther. 2020 Feb;11(2):479-494. doi: 10.1007/s13300-019-00750-8

Onwuchuluba EE, Oyetunde OO, Soremekun RO. Medication Adherence in Type 2 Diabetes Mellitus: A Qualitative Exploration of Barriers and Facilitators From Socioecological Perspectives. J Patient Exp. 2021 Jul 26;8:23743735211034338. doi: 10.1177/23743735211034338

American Diabetes Association Professional Practice Committee; 5. Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2022. Diabetes Care 1 January 2022; 45 (Supplement_1): S60–S82. https://doi.org/10.2337/dc22-S005

American Diabetes Association Professional Practice Committee; 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2022. Diabetes Care 1 January 2022; 45 (Supplement_1): S125–S143. https://doi.org/10.2337/dc22-S009

Perkumpulan Endokrinologi Indonesia. Pedoman Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia 2021. Jakarta: PB PERKENI; 2021. 119 p.

Olagbemide OJ, Omosanya OE, Ayodapo AO, Agboola SM, Adeagbo AO, Olukokun TA. Family Support and Medication Adherence Among Adult Type 2 Diabetes: Any Meeting Point? Ann Afr Med. 2021 Oct-Dec;20(4): 282-287. doi: 10.4103/aam.aam_62_20

Ranjbaran S, Shojaeizadeh D, Dehdari T, Yaseri M, Shakibazadeh E. Determinants of Medication Adherence Among Iranian Patients with Type 2 Diabetes: An Application of Health Action Process Approach. Heliyon. 2020 Jul 14;6(7):e04442. doi: 10.1016/j.heliyon.2020.e04442

Kementerian Kesehatan RI. Laporan Nasional RISKESDAS 2018. Jakarta: Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan; 2019. 1–674 p.

Masruroh NL, Pangastuti AF, Melizza N, Kurnia AD. Level of Knowledge and Family Support Toward Medication Adherence Among Patient with Diabetes Mellitus in Malang, Indonesia. Indian Journal of Forensic Medicine and Toxicology. 2021;15(1):1406–13.

Green LW, Kreuter MWTATT. Health program planning: An Educational And Ecological Approach. 4th ed. New York: McGraw-Hill; 2005.

Pender NJ, Murdaugh CL, Parsons MA. Health Promotion in Nursing Practice. 7th ed. Pender NJ, Murdaugh CL, Parsons MA, editors. New Jersey: Pearson Education, Inc; 2015.

AlShayban DM, Naqvi AA, Alhumaid O, AlQahtani AS, Islam MA, Ghori SA, Haseeb A, Ali M, Iqbal MS, Elrggal ME, Ishaqui AA, Mahmoud MA, Khan I, Jamshed S. Association of Disease Knowledge and Medication Adherence Among Out-Patients With Type 2 Diabetes Mellitus in Khobar, Saudi Arabia. Front Pharmacol. 2020 Feb 20;11:60. doi: 10.3389/fphar.2020.00060

Pourhabibi N, Mohebbi B, Sadeghi R, Shakibazadeh E, Sanjari M, Tol A, Yaseri M. Factors Associated with Treatment Adherence to Treatment Among in Patients with Type 2 Diabetes in Iran: A Cross-Sectional Study. Front Public Health. 2022 Nov 1;10:976888. doi: 10.3389/fpubh.2022.976888

Kokoszka A. Treatment Adherence in Patients with Type 2 Diabetes Mellitus Correlates with Different Coping Styles, Low Perception of Self-Influence on Disease, and Depressive Symptoms. Patient Prefer Adherence. 2017 Mar 17;11:587-595. doi: 10.2147/PPA.S124605

Kumar N, Unnikrishnan B, Thapar R, Mithra P, Kulkarni V, Holla R, Bhagawan D, Kumar A, Aithal S. Distress and Its Effect on Adherence to Antidiabetic Medications Among Type 2 Diabetes Patients in Coastal South India. J Nat Sci Biol Med. 2017 Jul-Dec;8(2):216-220. doi: 10.4103/0976-9668.210008

Jannoo Z, Wah YB, Lazim AM, Hassali MA. Examining Diabetes Distress, Medication Adherence, Diabetes Self-Care Activities, Diabetes-Specific Quality of Life and Health-Related Quality of Life Among Type 2 Diabetes Mellitus Patients. J Clin Transl Endocrinol. 2017 Jul 26;9:48-54. doi: 10.1016/j.jcte.2017.07.003s

Kretchy IA, Koduah A, Ohene-Agyei T, Boima V, Appiah B. The Association between Diabetes-Related Distress and Medication Adherence in Adult Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study. J Diabetes Res. 2020 Mar 1;2020:4760624. doi: 10.1155/2020/4760624.

Polonsky WH, Henry RR. Poor Medication Adherence in Type 2 Diabetes: Recognizing The Scope of The Problem and Its Key Contributors. Patient Prefer Adherence. 2016 Jul 22;10:1299-307. doi: 10.2147/PPA.S106821. PMID: 27524885; PMCID: PMC4966497.

Freeman-Hildreth Y, Aron D, Cola PA, Wang Y. Coping with Diabetes: Provider Attributes that Influence Type 2 Diabetes Adherence. PLoS One. 2019 Apr 2;14(4):e0214713. doi: 10.1371/journal.pone.0214713

Turen S, Yilmaz RA, Gundogdu S. The Relationship with Acceptance of Illness and Medication Adherence in Type 2 Diabetes Mellitus Patients. Int J Caring Sci. 2021;14(3):1824–32.

Fall E, Chakroun-Baggioni N, Böhme P, Maqdasy S, Izaute M, Tauveron I. Common Sense Model of Self-Regulation for Understanding Adherence and Quality of Life in Type 2 Diabetes with Structural Equation Modeling. Patient Educ Couns. 2021 Jan;104(1):171-178. doi: 10.1016/j.pec.2020.06.023

Albai A, Sima A, Papava I, Roman D, Andor B, Gafencu M. Association Between Coping Mechanisms and Adherence to Diabetes-Related Self-Care Activities: A Cross-Sectional Study. Patient Prefer Adherence. 2017 Jul 17;11:1235-1241. doi: 10.2147/PPA.S140146.

Świątoniowska-Lonc N, Tański W, Polański J, Jankowska-Polańska B, Mazur G. Psychosocial Determinants of Treatment Adherence in Patients with Type 2 Diabetes - A Review. Diabetes Metab Syndr Obes. 2021 Jun 16;14:2701-2715. doi: 10.2147/DMSO.S308322

Aronson BD, Sittner KJ, Walls ML. The Mediating Role of Diabetes Distress and Depressive Symptoms in Type 2 Diabetes Medication Adherence Gender Differences. Health Educ Behav. 2020 Jun;47(3):474-482. doi: 10.1177/1090198119885416

Supriati L, Handayani Nasution T, Andrian Ilmansyah F. Hubungan Dukungan Keluarga dengan Kejadian Depresi pada Pasien Diabetes Mellitus di Rumah Sakit Muhammadiyah Gresik. Majalah Kesehatan. 2016;3(4):183–9.

Molalign Takele G, Weharei MA, Kidanu HT, Gebrekidan KG, Gebregiorgis BG. Diabetes Self-Care Practice and Associated Factors Among Type 2 Diabetic Patients in Public Hospitals of Tigray regional state, Ethiopia: A multicenter study. PLoS One. 2021 Apr 21;16(4):e0250462. doi: 10.1371/journal.pone.0250462. PMID: 33882117; PMCID: PMC8059799.

Yang C, Lee DTF, Wang X, Chair SY. Effects of a Nurse-Led Medication Self-Management Intervention on Medication Adherence and Health Outcomes in Older People with Multimorbidity: A Randomised Controlled Trial. Int J Nurs Stud. 2022 Oct;134:104314. doi: 10.1016/j.ijnurstu.2022.104314

American Diabetes Association Professional Practice Committee; 6. Glycemic Targets: Standards of Medical Care in Diabetes—2022. Diabetes Care 1 January 2022; 45 (Supplement_1): S83–S96. https://doi.org/10.2337/dc22-S006

Mishra R, Sharma SK, Verma R, Kangra P, Dahiya P, Kumari P, Sahu P, Bhakar P, Kumawat R, Kaur R, Kaur R, Kant R. Medication Adherence and Quality of Life Among Type-2 Diabetes Mellitus Patients in India. World J Diabetes. 2021 Oct 15;12(10):1740-1749. doi: 10.4239/wjd.v12.i10.1740

Afaya RA, Bam V, Azongo TB, Afaya A, Kusi-Amponsah A, Ajusiyine JM, Abdul Hamid T. Medication Adherence and Self-Care Behaviours Among Patients with Type 2 Diabetes Mellitus in Ghana. PLoS One. 2020 Aug 21;15(8):e0237710. doi: 10.1371/journal.pone.0237710

Klinovszky A, Kiss IM, Papp-Zipernovszky O, Lengyel C, Buzás N. Associations of Different Adherences in Patients with Type 2 Diabetes Mellitus. Patient Prefer Adherence. 2019 Mar 15;13:395-407. doi: 10.2147/PPA.S187080

Huang YM, Shiyanbola OO, Smith PD. Association of Health Literacy and Medication Self-Efficacy with Medication Adherence and Diabetes Control. Patient Prefer Adherence. 2018 May 10;12:793-802. doi: 10.2147/PPA.S153312

Milky G, Thomas J 3rd. Shared Decision Making, Satisfaction with Care and Medication Adherence Among Patients with Diabetes. Patient Educ Couns. 2020 Mar;103(3):661-669. doi: 10.1016/j.pec.2019.10.008

Chlebowy DO, Batscha C, Kubiak N, Crawford T. Relationships of Depression, Anxiety, and Stress with Adherence to Self-Management Behaviors and Diabetes Measures in African American Adults with Type 2 Diabetes. J Racial Ethn Health Disparities. 2019 Feb;6(1):71-76. doi: 10.1007/s40615-018-0500-3

Escobar Florez OE, Aquilera G, De la Roca-Chiapas JM, Macías Cervantes MH, Garay-Sevilla ME. The Relationship Between Psychosocial Factors and Adherence to Treatment in Men, Premenopausal and Menopausal Women with Type 2 Diabetes Mellitus. Psychol Res Behav Manag. 2021 Dec 11;14:1993-2000. doi: 10.2147/PRBM.S342155

Rothman RL, Malone R, Bryant B, Wolfe C, Padgett P, DeWalt DA, Weinberger M, Pignone M. The Spoken Knowledge in Low Literacy in Diabetes Scale: a Diabetes Knowledge Scale for Vulnerable Patients. Diabetes Educ. 2005 Mar-Apr;31(2):215-24. doi: 10.1177/0145721705275002

Hamby S, Grych JH, Banyard V. Coping Scale. TN: Life Paths Research Program. 2015.

Hensarling J. Development and psychometric testing of Hensarling's Diabetes Family Support Scale. Dissertation. Repository TWU. Online. 2009. https://twu-ir.tdl.org/items/1abf63c4-2326-4b34-839b-aaec75bae1fd

Rondhianto, Nursalam, Kusnanto, Melaniani S, Ahsan. Analysis of the Sociodemographic and Psychological Factors of the Family Caregivers ’ Self-Management Capabilities for Type 2 Diabetes Mellitus. Jurnal Ners. 2019;14(2):215–23.

Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive Validity of a Medication Adherence Measure in an Outpatient Setting. J Clin Hypertens (Greenwich). 2008 May;10(5):348-54. doi: 10.1111/j.1751-7176.2008.07572.x. Retraction in: J Clin Hypertens (Greenwich). 2023 Sep;25(9):889. doi: 10.1111/jch.14718. Retraction in: J Clin Hypertens (Greenwich). 2023 Sep;25(9):890. doi: 10.1111/jch.14712

Assari S, Moghani Lankarani M, Piette JD, Aikens JE. Socioeconomic Status and Glycemic Control in Type 2 Diabetes; Race by Gender Differences. Healthcare (Basel). 2017 Nov 1;5(4):83. doi: 10.3390/healthcare5040083

Khan MS, B GS, Singh AK, Saxena S, Ahmad A. Sociodemographic and Anthropometric Factors Influencing Diabetes Mellitus in an Urban Population of District Bareilly: A Cross-Sectional Study. Int J Med Sci Public Health. 2020; 9(4): 267-272. doi:10.5455/ijmsph.2020.02022202025022020

Heerman WJ, Wallston KA, Osborn CY, Bian A, Schlundt DG, Barto SD, Rothman RL. Food Insecurity is Associated with Diabetes Self-Care Behaviours and Glycaemic Control. Diabet Med. 2016 Jun;33(6):844-50. doi: 10.1111/dme.12896

Zhang ZP, Premikha M, Luo M, Venkataraman K. Diabetes Distress and Peripheral Neuropathy are Associated with Medication Non-Adherence in Individuals with Type 2 Diabetes in Primary Care. Acta Diabetol. 2021 Mar;58(3):309-317. doi: 10.1007/s00592-020-01609-2

Supriati L, Kusumaningrum BR, Setiawan HF. Hubungan Tingkat Kecerdasan Emosional dengan Tingkat Stres pada Penderita Diabetes Mellitus di Rumah Sakit Tentara Dr. Soepraoen Malang. Majalah Kesehatan. 2017; 4(2):79–87.

Firani NK. Pengendalian Diabetes Mellitus Melalui Edukasi Pemantauan Kesehatan Mandiri dengan Panduan Buku Saku. Majalah Kesehatan. 2022; 9(1):29–36.

Downloads

Published

16-04-2025

Issue

Section

Original Research Article

How to Cite

PENGARUH DETERMINAN PSIKOSOSIAL TERHADAP PERILAKU KEPATUHAN PENGOBATAN  PADA PENDERITA DIABATES MELITUS TIPE 2. (2025). Majalah Kesehatan , 12(1), 8-20. https://doi.org/10.21776/majalahkesehatan.2025.012.01.2